Myocardial and Pericardial Diseases encompass a broad spectrum of structural, inflammatory, metabolic and immune-mediated conditions that significantly influence cardiac performance, ventricular interactions and clinical outcomes. Myocardial disorders such as cardiomyopathies, myocarditis and infiltrative diseases alter contractility, compliance and electrical stability, while pericardial pathologies—including pericarditis, pericardial effusion, constrictive pericarditis and tamponade—affect cardiac filling and hemodynamic equilibrium. As clinical presentations often overlap, accurate differentiation requires refined diagnostic expertise, which is why clinicians increasingly seek specialised educational resources and expert-led cardiology conference sessions that provide clarity on evolving diagnostic tools, biomarkers and multimodality imaging strategies. Given the shared anatomical and physiological relationships between myocardium and pericardium, an integrated understanding of these diseases is essential for optimal patient care.

Biomarkers remain central to early evaluation, with troponin, BNP, inflammatory markers and autoimmune panels guiding initial assessment. Imaging—including echocardiography, cardiac MRI, CT and nuclear modalities—plays a pivotal role in characterising structural changes, tissue composition, inflammation and pericardial thickening. Because many of these disorders intersect with cardiomyopathy diagnostics, this session highlights how MRI sequences, late gadolinium enhancement patterns, mapping techniques and strain analysis differentiate ischemic from non-ischemic etiologies. Participants will gain insight into how pericardial calcification, loculated effusions and chamber interdependence modify hemodynamic findings and influence treatment choices.

Management strategies vary widely depending on the underlying cause. Acute pericarditis often responds to NSAIDs, colchicine and corticosteroids, while chronic constrictive pericarditis may require pericardiectomy. Myocardial diseases range from reversible inflammatory processes to progressive infiltrative disorders requiring advanced therapies. Attendees will explore how genetic testing, tissue characterisation and endomyocardial biopsy support complex diagnoses and guide targeted therapy. Case-based discussions illustrate how to recognise red flags, initiate appropriate investigations and integrate multidisciplinary consultation.

This session also investigates systemic diseases that frequently impact myocardium and pericardium, such as autoimmune disorders, metabolic conditions, infections and infiltrative processes like amyloidosis or sarcoidosis. Understanding multisystem patterns allows clinicians to broaden differential diagnoses and tailor therapy. Participants will also learn how arrhythmias, conduction disturbances, heart failure symptoms and pericardial pain syndromes intersect with the underlying pathology.

Future directions include the expanding role of precision medicine, advanced MRI mapping algorithms, biologic therapies, novel anti-inflammatory agents and catheter-based interventions for effusive and constrictive disease. Clinicians will leave with a comprehensive understanding of the broad, interconnected spectrum of myocardial and pericardial pathologies and the tools required for accurate diagnosis and effective management.