Heart failure is a clinical syndrome caused by a structural and/or functional cardiac abnormality, resulting in a reduced cardiac output and/or elevated intracardiac pressures at rest or during stress.¹

Heart failure poses a significant global disease burden, more than 60 million patients worldwide have heart failure. Approximately 50% of patients diagnosed with heart failure will die within 5 years^2-3 .

There are 589 million patient with diabetes mellitus all over the world .⁴ People with diabetes have a 2- to 5-fold higher risk of developing HF ⁵ , On the other hand more than 30% of patients with heart failure also have diabetes.⁶

Patients with heart failure and diabetes have a worse prognosis than those without diabetes ⁶.

Prognosis of Patient with HF Following a Worsening HF event is Characterized by Repeated HF Event Despite the Use of Current Therapy. Resulting in Reduced Cardiac Function and Associated with Increase Mortality Risk, So early screening of HF in diabetic patient is important⁷

That is why 2024 ADA Guidelines for the first time that the use of cardiac biomarkers for HF risk prediction has been included in diabetic patient

ADA Standards of Care in Diabetes—2025 Consider screening adults with diabetes by measuring a natriuretic peptide (B-type natriuretic peptide [BNP] or N-terminal pro-BNP [NT-proBNP]) annually to facilitate prevention of stage C heart failure.

Refrences:
1-    Ponikowski P et al. Eur J Heart Fail 2016;18:891
2-    GBD 2016 Disease . Lancet 2017;390:1211;
3-    Mozaffarian D et al. Circulation 2016;133:e38
4-    IDF tenth edition 2025
5-    Kannel WB et al. Am J Cardiol 1974;34:29;
6-    MacDonald MR et al. Eur Heart J 2008;29:1377
7-    Jama Cardiology.2018.3,252-259
8-    Cardiovascular Disease and Risk Management: 
        Standards of Care in Diabetes - 2025 Diabetes Care 2025;

To be updated shortly..