As the use of pacemakers, implantable cardioverter defibrillators, and cardiac resynchronization devices expands, Cardiac Device Infection has become a critical complication with substantial morbidity and mortality. This session examines the spectrum of infection—from superficial pocket inflammation to systemic device-related endocarditis—and outlines evidence-based strategies for diagnosis, treatment, and prevention. Participants will review risk factors, microbiology, and clinical presentations, learning how to recognize early warning signs and differentiate sterile inflammation from true infection. The content is highly practical, geared toward cardiologists, electrophysiologists, infectious disease specialists, and device clinic teams.

Growing interest in a dedicated cardiology conference reflects the need for clearer, multidisciplinary pathways. This session discusses appropriate use of blood cultures, inflammatory markers, and advanced imaging such as transesophageal echocardiography and PET-CT to identify lead and valvular involvement. Attendees will learn when conservative management is inadequate and how to time complete system extraction, including leads, to maximize cure rates. Real-world case discussions highlight scenarios such as late pocket infections, occult bacteremia with implanted hardware, and device infection in frail or high-risk patients where procedural risk must be weighed carefully.

A central focus is best practice in CIED infection management (cardiac implantable electronic device infection). Participants will explore recommended antibiotic regimens, timing of re-implantation, and options for temporary pacing or defibrillation support during the interval. The session emphasizes the importance of referral to experienced extraction centers, where surgical and percutaneous expertise can be combined for complex cases. Preventive strategies—antibiotic prophylaxis, pocket preparation, device selection, and use of antibacterial envelopes—are discussed in detail to help reduce first-time and recurrent infections.

The session also covers system-wide implications, including the role of device infection registries, standardized documentation, and quality improvement initiatives. Attendees will learn how to design institutional protocols that streamline referrals, clarify responsibilities among specialties, and ensure timely intervention. By the end, participants will have a comprehensive framework for recognizing, treating, and preventing cardiac device infections, ultimately safeguarding the benefits of device therapy for patients who depend on them.