Rapid advances in genetics are transforming how we understand inherited and complex cardiovascular diseases, and Cardio Genomics sits at this cutting edge. This session explores how single-gene disorders, polygenic risk, and gene–environment interactions contribute to conditions such as cardiomyopathies, arrhythmia syndromes, aortopathies, and premature coronary disease. Participants will learn when to suspect a genetic basis, how to order and interpret tests, and how to integrate results into personalised management plans. Emphasis is placed on bridging the gap between laboratory reports and bedside decisions.

Clinicians increasingly seek a cardiology conference to navigate quickly evolving testing options. This session reviews targeted gene panels, whole exome and genome sequencing, and polygenic risk scores, clarifying which tools are appropriate for different scenarios. Attendees will examine interpretation frameworks that distinguish pathogenic variants from benign polymorphisms and variants of uncertain significance. Real-world cases highlight challenges such as incomplete penetrance, variable expressivity, and family members with differing risk profiles despite similar genotypes.

A key focus is developing robust genetic cardiology services that combine clinical expertise with genetic counselling. Participants will explore workflows for cascade screening of relatives, cardiology–genetics co-clinics, and shared decision-making around preventive therapies or device implantation. The session addresses ethical considerations, including incidental findings, reproductive counselling, and data privacy. Strategies are discussed for communicating complex genetic information in understandable language, supporting patients as they process risk, uncertainty, and implications for family members.

Looking forward, the session touches on emerging directions such as gene editing, RNA-based therapies, and refined polygenic risk models for common conditions like coronary artery disease and atrial fibrillation. By the end, attendees will be better equipped to identify patients who may benefit from genomic evaluation, interpret test results responsibly, and integrate cardio genomics into contemporary cardiac care.