The field of Cardiovascular Science and Medicine synthesizes foundational discovery with clinical application to advance understanding of heart and vascular biology, diagnostics and therapeutics. This session brings together basic scientists, translational researchers and clinicians to examine mechanisms of disease, novel diagnostic strategies and pathway-driven treatments. Participants will explore how molecular and cellular insights inform systems-level understanding of cardiac function and dysfunction, and how these insights translate into improved patient care. Sessions will highlight cross-disciplinary advances—from computational hemodynamics and multi-omics profiling to device innovation and biomarker validation—providing attendees with actionable knowledge to design better studies, optimize diagnosis, and implement evidence-based therapies. Delegates will gain practical perspectives on regulatory pathways, trial design and collaborative frameworks that accelerate promising discoveries into real-world impact. Join peers to discuss reproducible methods, trial endpoints, and the clinical interpretation of complex datasets that bridge laboratory findings and bedside decision-making — and deep-dive into Cardiovascular Science Conference themes including bench-to-bedside pathways, translational pipelines and systems cardiology. Special sessions focus on diagnostics and prognostics through cardiac biomarkers, advanced imaging and integrative modeling to enhance risk stratification and therapeutic targeting