Coronary Physiology provides the essential foundation for understanding myocardial perfusion, flow dynamics, microvascular behavior, and pressure–flow relationships that guide decision-making in interventional and clinical cardiology. This session explores the tools, principles, and real-world applications of physiological assessment, helping clinicians accurately determine lesion significance beyond anatomical imaging. As specialists increasingly search for a dedicated cardiology conference, this session connects physiology concepts with practical algorithms used in modern PCI and patient evaluation.

The description highlights key physiological indices, including Fractional Flow Reserve (FFR), instantaneous wave-free ratio (iFR), Pd/Pa, resting full-cycle ratio (RFR), coronary flow reserve (CFR), and microvascular resistance measurements. Participants will learn the mechanisms behind pressure-wire assessment, hyperemia induction, and the impact of hemodynamic variations. Case-based interpretation clarifies how physiology identifies ischemia-producing lesions that angiography alone cannot detect.

A major component focuses on implementing advanced coronary physiology strategies in clinical workflows. Participants will explore when to use FFR vs. iFR, how to interpret borderline values, how to assess serial lesions, and how to evaluate diffuse atherosclerosis. The session also emphasizes the importance of evaluating microvascular dysfunction, which explains symptoms in patients with normal angiography but abnormal physiology.

The description discusses how physiology improves PCI outcomes through better lesion selection, fewer unnecessary stents, optimized revascularization plans, and guidance for complete vs. ischemia-driven PCI. Participants will learn to integrate physiologic findings into heart team decisions, chronic coronary syndrome evaluation, and post-PCI optimization. The session also covers catheter manipulation, drift correction, pullback techniques, and identifying pressure-wire artifacts.

Emerging topics include AI-assisted physiologic interpretation, non-invasive FFR derived from CT (FFR-CT), angiography-derived FFR, fiber-optic sensors, and hybrid imaging-physiology systems. By the end, attendees will feel confident using coronary physiology to guide precise, evidence-based treatment.