Fractional Flow Reserve (FFR) is a gold-standard physiologic index used to determine the ischemic significance of coronary lesions. This session provides a complete understanding of FFR principles, wire-based measurement, pressure dynamics, and interpretation techniques. As physiology-guided PCI becomes essential globally, clinicians increasingly seek a focused cardiology conference to enhance interventional decision-making.

The description explains that FFR quantifies pressure differences across a coronary stenosis during hyperemia, producing a reproducible index that strongly correlates with clinical outcomes. Participants will learn the science behind hyperemic agents, microcirculatory function, and flow resistance. The session explores differences between FFR, iFR, and related indices, emphasizing how to select the right tool for each patient.

A central focus is applying advanced FFR assessment strategies in diffuse disease, serial lesions, left main stenosis, multivessel CAD, and borderline lesions. The session covers interpreting pullback curves, identifying pressure step-ups, managing drift, and determining lesion-specific ischemia. Case-based discussions clarify when to revascularize and when to avoid unnecessary PCI.

Participants will also learn how FFR impacts long-term outcomes—reducing stent use, preventing complications, and improving survival. The session covers integration of FFR into heart team meetings, chronic coronary syndrome evaluation, and procedural planning.

Future advances include angiography-derived FFR, CT-derived FFR (FFR-CT), AI-driven analysis, and novel fiber-optic pressure sensors.