Dilated Cardiomyopathy

Dilated Cardiomyopathy (DCM) is a progressive myocardial disorder characterized by ventricular dilation, impaired systolic function, and eventual heart failure. This session explores genetic, inflammatory, metabolic, and idiopathic contributors to DCM, emphasizing early recognition, precise diagnosis, and evidence-based management. As clinicians increasingly seek a focused cardiology conference, this session provides in-depth insight into the full DCM spectrum.

The description begins with DCM pathophysiology, examining how sarcomeric mutations, viral myocarditis, autoimmune injury, toxins, endocrine abnormalities, alcohol, and metabolic disturbances weaken myocardial structure. Participants will explore how remodeling leads to chamber dilation, reduced contractility, mitral regurgitation, arrhythmias, and progressive heart failure.

Diagnosis includes clinical evaluation, ECG, echocardiography, CMR with late gadolinium enhancement, strain imaging, coronary evaluation, genetic testing, and targeted laboratory studies. The session explains how to differentiate DCM from ischemic cardiomyopathy, peripartum cardiomyopathy, tachycardia-induced cardiomyopathy, and infiltrative disease.

A major emphasis focuses on implementing advanced dilated cardiomyopathy management strategies. Participants will learn guideline-directed medical therapy, including ARNI, beta-blockers, MRAs, SGLT2 inhibitors, diuretics, and vasodilators. The content addresses arrhythmia risk, indications for ICD or CRT, antiarrhythmic approaches, and management of atrial fibrillation in DCM.

Case-based discussions highlight when to pursue genetic evaluation, how to manage familial DCM, and how to monitor high-risk features such as mid-wall fibrosis. Participants will explore advanced options including LVAD, mechanical support, and transplant referral for refractory cases.

Future directions include gene therapy, targeted molecular therapy, precision medicine based on genotype, and AI-supported prognostic models. This session provides a comprehensive framework for improving outcomes in DCM patients.

Core Concepts in DCM

Pathophysiological Mechanisms

  • Examining genetic, inflammatory, and toxic contributors.
  • Understanding remodeling and progression to HF.

Diagnostic Approaches

  • Using echo, CMR, and genetic testing.
  • Differentiating DCM from other cardiomyopathies.

Medical and Device Therapies

  • Implementing GDMT effectively.
  • Selecting ICD/CRT in high-risk patients.

Monitoring and Prognosis

  • Tracking fibrosis, arrhythmia risk, and functional change.
  • Planning timely referral for advanced therapies.

Clinical and Patient Advantages

Earlier Identification of High-Risk Patients
Imaging and genetics detect disease before severe dysfunction.

Reduced Heart Failure Burden
Therapy slows progression and improves symptoms.

Lower Mortality Through Timely Intervention
Device therapy and advanced options improve survival.

Better Family Screening
Genetic insights guide evaluation of relatives.

Enhanced Treatment Precision
Phenotyping supports personalized care.

 

Better Long-Term Quality of Life
Comprehensive care improves daily functioning.

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